Tuesday, March 6, 2007

Spray Tan After Getting Legs Waxed

nanoscale engineering nanomedicine. 18/25. Global health as a "great challenge"

Nanotechnology has already changed the way to make some drugs and in some cases, rewritten. When a pharmaceutical compound is formulated as a nanoparticle, increasing their level of bioavailability. In other words, the body can absorb a compound, well made, the quicker and easier, and as such use more effectively, if the compound exists on a scale closer to the scale at which biological processes occur. The level of bioavailability of a drug is an important element to determine its effectiveness. A market research firm estimates to 65 billion dollars annual revenue from the drug market (almost 16 percent of total sales of the pharmaceutical industry) come from drugs that have low bioavailability, which promotes higher costs for patients, treatment ineffective and an increased risk of toxicidad.27

Elan Corporation, headquartered in Dublin, Ireland, has developed a patented process to "grind" pharmaceuticals and produce small particles (typically below 100 nm) that have a greater bioavailability and faster absorption rates, according to reports from the very compañía.28 Elan also asserts that the newly formulated drug Nanomedicine eliminate the "variability fasting / satiety (ie, that matters less if the drug is taken with food). Large pharmaceutical companies like Wyeth, Merck and Abbott and gave their proprietary compounds to Elan for "wheel." In most cases, the drugs and had the U.S. FDA approval in their formulations and larger, and as companies can demonstrate the "bioequivalence" 29-that the difference in the action of the drug from its former and the new wording is "medically insignificant" - the new Nanomedicine version is not subjected to more regulatory scrutiny, as it would if more evidence were asked clínicas.30
The pharmaceutical formulations rely on their nano-particles to improve the therapeutic value of "low-performing drugs, but also seeking to improve their profits. It is possible that older drugs that are no longer in the market for its low efficacy or potentially serious adverse effects in certain patient populations may be more effective or safer if reformulated nanoscale, thereby significantly decreasing the cost of the process drug development. Companies pharmaceutical and take advantage of the expansion of patent protection, which is possible through their formulations nano-particuladas.31 Even in cases that can be demonstrated bioequivalence between a drug and its counterpart nanoscale-and become more necessary clinical trials exist in the U.S. a strategic advantage: the possessor of a patent is granted a period of three to five years of "off-patent exclusivity, the drug while undergoing retesting clínicos.32 This period is independent of patent rights and benefits the big drug companies because it keeps in line by the companies that produce generic drugs
baratos.33
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